The Cities of Eternal Fog
This potent ritual taints the blood of its target, whether mortal or vampire. Roll Manipulation + Occult + Crúac in a contested action against the target’s Stamina + Blood Potency (resistance is reflexive). If the roll for the caster gets the most successes, that number of successes is inflicted as lethal damage to a mortal target.
A vampire target immediately loses the equivalent of Vitae in his system and could be subject to frenzy as a result. Indeed, a vampiric victim might be forced into torpor. The caster must be able to see the intended victim when the ritual is performed.